200-301-W57
LAR/PTPRF Antibody
Cannot supply to this region.
- SKU:
- 200-301-W57
- Additional Names:
- LAR/PTPRF|Receptor-type tyrosine-protein phosphatase F, Leukocyte antigen related (LAR), FLJ43335, FLJ45062, FLJ45567, LAR, LAR protein, LARFN5C, LARS, LCA homolog, Leukocyte antigen related (LAR) PTP receptor, Leukocyte antigen related tyrosine phosphatase, Leukocyte common antigen related
- Application:
- ELISA, IHC, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Mouse
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-LAR/PTPRF Antibody was produced in mice by repeated immunizations of a fusion peptide consisting of amino acids 1315-1607 of human LAR.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Clone:
- S165-38
- Uniprot:
- P10586
- Synonyms:
- BNAH2;LAR;LCA-homolog;leukocyte antigen-related (LAR) PTP receptor;leukocyte antigen-related tyrosine phosphatase;leukocyte common antigen related;protein tyrosine phosphatase, receptor type, F polypeptide;receptor-linked protein-tyrosine phosphatase LAR;receptor-type tyrosine-protein phosphatase F
- Extra Details:
- PTPRF or leukocyte common antigen-related protein (LAR) is a widely expressed protein tyrosine phosphatase with an extracellular receptor region that resembles a cell adhesion molecule. PTPRF removes phosphate group from B Beta-catenin, an event that may subsequently facilitate cell-cell adhesion and ensure the stability of the cadherin complex. This phosphatase has also been implicated in various cellular processes such as neurite growth, nerve regeneration, actin remodeling and regulation of insulin function (1,2,3,4). Anti-PTPRF (C-terminal) antibody is specific for the extracellular and cytoplasmic subunits of human PTPRF (approx. 210, 150 and 85 kDa). Detection of the PTPRF bands by immunoblotting is specifically inhibited by the immunizing peptide. Anti-PTPRF is ideal for researchers interested in Cell adhesion Cadherin-mediated cell adhesion pathways, PAK pathways, insulin resistance and ureterocele.
- Shipping Conditions:
- Blue Ice