200-301-MV4
Hemoglobin Antibody
Cannot supply to this region.
- SKU:
- 200-301-MV4
- Additional Names:
- HBA, HBB|Sickle Cell Disease (SCD), mouse anti-hemoglobin antibody
- Application:
- ELISA, WB, Lateral Flow
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-Hemoglobin (whole molecule) Monoclonal Antibody was produced in mice by repeated immunizations with a synthetic peptide corresponding to amino acid residues near the N-terminus of Hb B Beta-subunit conjugated to KLH.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Clone:
- 2B7.G10.H12
- Extra Details:
- Hemoglobin antibody detects the hemoglobin tetramer composed of alpha and beta subunits. Functional adult hemoglobin (Hb) is a hetero tetramer composed of 2 alpha and 2 beta subunits (A Alpha2B Beta2). Common isoform variants of hemoglobin include HbA, HbS, HbC, and HbA-2. Sickle cell disease (SCD), thalassemias and hemoglobinopathies occur when aberrant forms of hemoglobin are expressed in children and adults. Globin gene mutations affect the structure and expression levels of Hb. Sickle cell disease and the more benign sickle cell trait are observed in more than 100 million people globally. Perhaps the most significant mutation is the E6V in the beta subunit and the cause of SCD, but other relevant isoforms of Hb are observed. Hemoglobin antibody reacts whole hemoglobin tetramer. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.
- Shipping Conditions:
- Dry Ice