200-301-I25
TLR4 Antibody
Cannot supply to this region.
- SKU:
- 200-301-I25
- Additional Names:
- hToll, Toll-like receptor 4, CD284|TLR4
- Application:
- ChIP, ELISA, Flow Cytometry, IHC, WB, IF, Dot blot
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Mouse
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- TLR4 Antibody was produced in mice prepared by repeated immunizations with amino acids corresponding to an internal sequence in human TLR4.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Clone:
- 76B357.1
- Uniprot:
- O00206
- Synonyms:
- ARMD10;CD284;homolog of Drosophila toll;hToll;TLR-4;TOLL;toll like receptor 4 protein;toll-like receptor 4
- Extra Details:
- Anti-TLR4 CD284 antibody detects human TLR4 CD284. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. Among this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling. The TLR4 cDNA codes for a protein consisting of 799 amino acids with approximate molecular weight of 88 kDa. Anti-TLR4 CD284 antibody is ideal for investigators involved in cytokines and growth factor research.
- Shipping Conditions:
- Dry Ice