200-301-H80
IKB alpha Antibody
Cannot supply to this region.
- SKU:
- 200-301-H80
- Additional Names:
- IKBA, MAD3, NFKBI, NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3|NFKBIA
- Application:
- ChIP, Flow Cytometry, IHC, WB, IF, IP
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Mouse
- Reactivities:
- Human, Mouse
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- IkB alpha Antibody was produced in mice prepared by repeated immunizations of recombinant protein corresponding to internal amino acids in the human IkB alpha protein.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Clone:
- 6A920
- Uniprot:
- P25963
- Synonyms:
- EDAID2;I-kappa-B-alpha;IkappaBalpha;ikB-alpha;IKBA;MAD-3;major histocompatibility complex enhancer-binding protein MAD3;NF-kappa-B inhibitor alpha;NFKBI;nuclear factor of kappa light chain gene enhancer in B-cells;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
- Extra Details:
- Anti-IkB alpha detects human IkB alpha. NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. Synthesis of IkBa is autoregulated. IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/a, IKK2/b, and IKK3/g. External stimuli such as tumor necrosis factor or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified. One of the first gene induced following NF-kB activation is IkBa. Anti-IkB alpha antibody is ideal for investigators involved in NFkappaB, kinase and phosphatase research.
- Shipping Conditions:
- Dry Ice