Hemoglobin beta A-2 Antibody

Cannot supply to this region.

SKU:: 200-301-GS8
Additional Names:: HBD|mouse anti-HbA-2 antibody, mouse anti-hemoglobin antibody, Hemoglobin Subunit Delta, Hemoglobin Delta Chain 4, Delta-Globin 4, HbD, HbA-2 Antibody, Sickle Cell Disease (SCD)
Application:: ELISA, WB, Lateral Flow
Concentration:: 1.00 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Host:: Mouse
Reactivities:: Human
Buffer:: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
Immunogen:: Anti-Hemoglobin beta A-2 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus of Hb D Delta-subunit conjugated to KLH.
Formulation:: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Clone:: 21G1.F1.B9.G9.D11
Uniprot:: P02042
Synonyms:: delta globin;Delta-globin;delta-globin chain;hemoglobin delta chain;hemoglobin subunit delta;hemoglobin, delta
Extra Details:: HbA-2 or hemoglobin delta subunit antibodies detect the delta-specific sequence in the hemoglobin delta-subunit found in HbA-2. Functional hemoglobin (Hb) is a hetero tetramer and the dominant form of Adult Hb is composed of 2 alpha and 2 beta subunits (A Alpha2B Beta2). Hemoglobin A-2 (HbA-2) is a normal but minor variant of hemoglobin A that consists of two alpha and two delta chains (A Alpha2D Delta2). Hemoglobin A-2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene, and HbA2 is also linked to neurological disorders. HbA-2 form exists in small amounts in all adult humans (1.5-3.1% of all hemoglobin molecules) and is increased in people with Sickle-cell disease. Its normal biological role is not well understood. HbA-2 antibody does not react other forms of Hb including no cross-reaction to HbA or beta subunit. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.

Shipping Conditions:: Dry Ice