200-301-GS7
Hemoglobin beta C Antibody
Cannot supply to this region.
- SKU:
- 200-301-GS7
- Additional Names:
- HBBc|mouse anti-HbC antibody, mouse anti-hemoglobin antibody, Hemoglobin beta subunit C variant, HbBc, HbC, HbC Antibody, LVV-hemorphin-7, Spinorphin, Beta-globin, Hemoglobin beta chain, Sickle Cell Disease (SCD)
- Application:
- ELISA, WB, Lateral Flow
- Concentration:
- 1.00 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-Hemoglobin beta C Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus of Hb B Beta-subunit conjugated to KLH.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Clone:
- 15C2.C11.F2.G11
- Uniprot:
- P68871
- Synonyms:
- beta globin chain;beta-globin;CD113t-C;ECYT6;Hemoglobin beta chain;hemoglobin beta subunit;hemoglobin subunit beta;hemoglobin, beta
- Extra Details:
- HbC antibodies detect the E6K mutant in the hemoglobin beta subunit. Functional hemoglobin (Hb) is a hetero tetramer composed of 2 alpha and 2 beta subunits (A Alpha2B Beta2). Common isoform variants of hemoglobin include HbA, HbS, HbC, HbF, and HbA2. Sickle cell disease (SCD), thalassemias and hemoglobinopathies occur when aberrant forms of hemoglobin are expressed in children and adults. Globin gene mutations affect the structure and expression levels of Hb. Sickle cell disease and the more benign sickle cell trait are observed in more than 100 million people globally. Less significant than the SCD-E6V, HbC E6K mutation causes a mild hemolytic anemia. HbC antibody does not react to other forms of Hb. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.
- Shipping Conditions:
- Dry Ice