DMPO Antibody

Cannot supply to this region.

SKU:: 200-301-F21
Additional Names:: 5,5-dimethyl-2-(8-octanoic acid)-1-pyrroline N oxide
Application:: ELISA, IHC, WB, IF, IP
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Virus
Storage Conditions:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Rockland Inc
Host:: Mouse
Buffer:: 0.01 M Tris Cl, 0.15 M Sodium Chloride, 0.001 M EDTA
Immunogen:: DMPO Antibody was produced in mice by repeated immunizations with 5,5-dimethyl-2-(8-octanoic acid)-1-pyrrolone-N-oxide conjugated to Ovalbumin.
Formulation:: 0.01 M Tris Cl, 0.15 M Sodium Chloride, 0.001 M EDTA, pH 7.4
Clone:: N1664A
Extra Details:: The formation of free radicals and other highly reactive oxygen species has been implicated in the pathogenesis of many disease states. The ability to identify these species is crucial, and spin trapping has accomplished this goal. DMPO (5,5-dimethyl-1-pyrroline N-oxide) is one of the least toxic to cells and animals, and possesses convenient pharmacokinetics (uptake, distribution, metabolism and excretion) in biological systems. Recent studies have determined that nitric oxide may substantially affect the quantitative determination of DMPO adducts, and therefore extra caution is required when studying generation of these species in the presence of nitric oxide or its radicals. DMPO adducts can be generated with protein and DNA radicals.