100-4169
Esterase Antibody
Cannot supply to this region.
- SKU:
- 100-4169
- Additional Names:
- CES3|rabbit anti-Esterase Antibody, Liver carboxylesterase, Proline-beta-naphthylamidase, Retinyl ester hydrolase
- Application:
- ELISA, WB
- Concentration:
- 85 mg/ml
- Physical State:
- Lyophilized
- Species Reactivity:
- Porcine
- Storage Conditions:
- 2-8[o]C liquid. Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Porcine
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Esterase [Porcine Liver]
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Format:
- Antiserum
- Uniprot:
- Q29550
- Synonyms:
- carboxylesterase;carboxylesterase 3;liver carboxylesterase;liver carboxylesterase 1;liver carboxylesterase G2;PLE-1;PLE-G2;Proline-beta-naphthylamidase;Retinyl ester hydrolase
- Extra Details:
- Esterase is involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. It is active towards triacylglycerides containing short-chain fatty acids from C2 to C6, and 13-monoacylglycerols containing fatty acids from C2 to C12; and inactive on long-chain triacylglycerols and diacylglycerol. it hydrolyzes aromatic and alkyl esters and vitamin A acetate. The hydrolysis rate depends upon the amino acid promoiety and the esterification site of the prodrug. Aromatic promoieties are favored, highest rates are observed with phenylalanyl progdrugs, hydrolysis of valyl and isoleucyl prodrugs is less efficient. With floxuridine prodrugs, activity is higher on 5' monoesters than on 3' monoesters; while with gemcitabine prodrugs, activity is higher on 3' monoesters than on 5' monoesters.
- Shipping Conditions:
- Ambient