Jarid1b Antibody

Cannot supply to this region.

SKU:: 100-401-V92
Additional Names:: Kdm5b|Lysine-specific demethylase 5B, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1
Application:: ELISA, WB
Physical State:: Liquid
Species Reactivity:: Mouse
Storage Conditions:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Mouse
Immunogen:: Anti-Jarid1b Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing an amino acid sequence from the internal part of mouse Jarid1b.
Format:: Antiserum
Uniprot:: Q80Y84
Synonyms:: [histone H3]-trimethyl-L-lysine(4) demethylase 5B;2010009J12Rik;2210016I17Rik;AW556288;cancer/testis antigen 31;CT31;D1Ertd202;D1Ertd202e;histone demethylase JARID1B;Jari;JARID1B;jumonji, AT rich interactive domain 1B;jumonji, AT rich interactive domain 1B (Rbp2 like);jumonji/ARID domain-containing protein 1B;lysine (K)-specific demethylase 5B;lysine-specific demethylase 5B;mKIAA4034;MRT65;Pl;PLU;PLU-1;PLU1;PPP1R98;protein phosphatase 1, regulatory subunit 98;PUT1;putative DNA/chromatin binding motif;putative DNA/chromatin binding motif 1;Rb-B;Rb-Bp2;RBBP2H1A;RBP2-H1;retinoblastoma-binding protein 2 homolog 1;retinoblastoma-binding protein 2, homolog 1A
Extra Details:: JARID1B is a histone demethylase which specifically demethylates mono-, di, and trimethylated lysine 4 of histone H3. It acts as a transcriptional repressor for the tumor suppressor genes BRCA1 and HOXA5 and has been associated with breast cancer development. In contrast, in melanoma JARID1B itself may function as a tumor suppressor. Anti-Jarid1b Antibody is ideal for research in Epigenetics, Chromatin Remodeling and Cancer.

Shipping Conditions:: Dry Ice