Ash2 Antibody

Cannot supply to this region.

SKU:: 100-401-V87
Additional Names:: ASH2L|Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2-like protein, ASH2L1, ASH2L2, Bre2
Application:: ELISA, WB, IF
Physical State:: Liquid
Species Reactivity:: Mouse
Storage Conditions:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Mouse
Immunogen:: Anti-Ash2 Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides of mouse Ash2: two containing an amino acid sequence from the internal and one containing an amino acid sequence from the C-terminal part of the protein.
Format:: Antiserum
Uniprot:: Q9UBL3
Synonyms:: ASH2;ash2 (absent, small, or homeotic)-like;ASH2-like protein;ASH2L1;ASH2L2;Bre2;set1/Ash2 histone methyltransferase complex subunit ASH2
Extra Details:: Ash2 is a component of the Set1/Ash2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the Set1/Ash2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. Ash2 plays a role in hematopoiesis and may be associated with some kinds of leukemia. Anti-Ash2 Antibody is ideal for research in Gene Expression, Epigenetics, Cell Signaling and Cancer.