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100-401-V37

hLeo1 Antibody

Cannot supply to this region.

SKU:
100-401-V37
Additional Names:
LEO1|RNA polymerase-associated protein LEO1, Replicative senescence down-regulated leo1-like protein, RDL
Application:
WB
Physical State:
Liquid
Species Reactivity:
Human
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Host:
Rabbit
Reactivities:
Human
Immunogen:
Anti-hLeo1 Antibody was produced in rabbits by repeated immunizations with a full length recombinant protein of human Leo1 (component of the human PAF1/RNA polymerase ll complex).
Format:
Antiserum
Uniprot:
Q8WVC0
Synonyms:
Leo1 Paf1/RNA polymerase II complex component;Leo1, Paf1/RNA polymerase II complex component, homolog;RDL;replicative senescence down-regulated leo1-like protein;RNA polymerase-associated protein LEO1
Extra Details:
PAF is a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9, which was first purified from yeast. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. The human PAF (hPAF) complex shares four subunits with yPAF (hCtr9, hPaf1, hLeo1 and Cdc73), but contains an additional higher eukaryotic-specific subunit, hSki8. In addition to coordinating events during transcription (initiation, promoter clearance and elongation); PAF also coordinates events in RNA quality control. Anti-hLeo1 Antibody is ideal for research in Gene Expression, Transcription and Epigenetics.
Shipping Conditions:
Dry Ice