100-401-A15
APC11 Antibody
Cannot supply to this region.
- SKU:
- 100-401-A15
- Additional Names:
- ANAPC11|rabbit anti-Apc11 Antibody, Anaphase promoting complex subunit 11 homolog antibody, APC11 anaphase promoting complex subunit 11 homolog antibody, Cyclosome subunit 11 antibody, Hepatocellular carcinoma associated RING finger protein antibody, HSPC 214 antibody, Apc
- Application:
- ELISA, IHC, WB, IP
- Concentration:
- 85 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Immunogen:
- This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 76-84 of Human APC11 (C-terminal) coupled to KLH.
- Format:
- Antiserum
- Uniprot:
- Q9NYG5
- Synonyms:
- anaphase promoting complex subunit 11 (yeast APC11 homolog);anaphase-promoting complex subunit 11;APC11;APC11 anaphase promoting complex subunit 11 homolog;Apc11p;cyclosome subunit 11;hepatocellular carcinoma-associated RING finger protein;HSPC214
- Extra Details:
- APC11 is also known as Anaphase promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma associated RING finger protein, and HSPC214. APC11 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC11 may function to recruit the E2 ubiquitin-conjugating enzymes to the complex. APC11 interacts with the cullin domain of ANAPC2 and also interacts with UBE2D2. APC11 shows both a cytoplasmic and nuclear localization. APC11 is expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte. APC11 is a member of the RING-type zinc finger family and is auto-ubiquitinylated.
- Shipping Conditions:
- Dry Ice