SKP1 Antibody

Cannot supply to this region.

SKU:: 100-401-A08
Additional Names:: rabbit anti-SKP1 Antibody, Cyclin A/CDK2 associated protein p19 antibody, EMC 19 antibody, OCP 2 antibody, p19skp1 antibody, RNA polymerase II elongation factor like protein antibody, S phase kinase associated protein 1 antibody|SKP1
Application:: ELISA, IHC, WB, IP
Concentration:: 85 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Rockland Inc
Host:: Rabbit
Reactivities:: Human
Immunogen:: This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 152-163 of Human SKP1 (C-terminus) coupled to KLH.
Format:: Antiserum
Uniprot:: P63208
Synonyms:: cyclin A/CDK2-associated p19;cyclin-A/CDK2-associated protein p19;EMC19;OCP-2;OCP-II;OCP2;organ of Corti protein 2;organ of Corti protein II;p19A;p19skp1;RNA polymerase II elongation factor-like protein;RNA polymerase II elongation factor-like protein OCP2;S-phase kinase-associated protein 1;SIII;SKP1A;TCEB1L;transcription elongation factor B polypeptide 1-like
Extra Details:: SKP1 is also known as S-phase kinase-associated protein 1A, Cyclin A/CDK2-associated protein p19, p19A, p19skp1, RNA polymerase II elongation factor-like protein, Organ of Corti protein 2, OCP-II protein, OCP-2, Transcription elongation factor B, and SIII. SKP1 is an essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, SKP1 serves as an adapter that links the F-box protein to CUL1. SKP1 interacts directly with CUL1 and F-box proteins, such as BTRC and SKP2, in the SCF complex. SKP1 also interacts with FBX29 and the cyclin A/CDK2 complex. SKP1 is part of a SCF-like complex consisting of CUL7, RBX1, SKP1 and FBXW8 and is also a component of a E3 ubiquitin ligase complex containing UBE2D1, SIAH1, CACYBP/SIP, SKP1A, APC and TBL1X.

Shipping Conditions:: Dry Ice