100-401-A07
PARC Antibody
Cannot supply to this region.
- SKU:
- 100-401-A07
- Additional Names:
- CUL9|rabbit anti-PARC Antibody, p53 associated parkin like cytoplasmic protein antibody, RP3 330M21.2 antibody, UbcH 7 associated protein 1 antibody
- Application:
- ELISA, IHC, WB, IP
- Concentration:
- 85 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Immunogen:
- This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 2503-2517 of Human PARC (C-terminus) coupled to KLH.
- Format:
- Antiserum
- Uniprot:
- Q8IWT3, Q8IWT3.2
- Synonyms:
- CUL-9;cullin-9;H7AP1;p53-associated parkin-like cytoplasmic protein;PARC;parkin-like cytoplasmic p53 binding protein;UbcH7-associated protein 1
- Extra Details:
- Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. PARC is a cullin family member that functions as a cytoplasmic anchor protein in p53-associated protein complexes. PARC regulates the subcellular localization of p53 and subsequent function. PARC forms a complex with p53 in the cytoplasm of unstressed cells and interacts with UBCH7 and UBCH8. PARC shows a cytoplasmic localization and is ubiquitously expressed in all tissues with highest expression in testis brain and kidney.
- Shipping Conditions:
- Dry Ice