100-401-249
CIITA Antibody
Cannot supply to this region.
- SKU:
- 100-401-249
- Additional Names:
- CIITA|rabbit anti-CIITA Antibody, MHC class II transactivator, CIITA, MHC2TA
- Application:
- ChIP, ELISA, WB, IP
- Concentration:
- 90 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Immunogen:
- The immunogen used for this study was a bacterially produced recombinant FLAG-CIITA corresponding to amino acids 1 through 333 of the human protein.
- Format:
- Antiserum
- Uniprot:
- P33076
- Synonyms:
- C2TA;CIITAIV;MHC class II transactivator;MHC class II transactivator type I;MHC class II transactivator type III;MHC2TA;NLR family, acid domain containing;NLRA;nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing
- Extra Details:
- Anti-CIITA antibody detects CIITA. The transactivator CIITA regulates basal and interferon-induced expression of Major Histocompatibility Complex class II genes. CIITA restores expression of all MHC class II gene expression in mutant cells and corrects regulatory defects of MHC class II genes. Antibodies to this transactivator are useful in the study of diseases of pathological MHC class II expression. Antigen can be obtained from Raji cell lysates. Typically levels of CIITA expression are too low to detect endogenous levels of protein expression. Transiently transfected cells are usually employed to study this transcription factor.
- Shipping Conditions:
- Dry Ice