100-401-170
p16 Antibody
Cannot supply to this region.
- SKU:
- 100-401-170
- Additional Names:
- CDKN2A|rabbit anti-p16 Antibody, Cyclin-dependent kinase inhibitor 2A isoforms 1/2/, Cyclin-dependent kinase 4 inhibitor A, CDK4I, p16-INK4a, p16INK4A, p16-INK4, Multiple tumor suppressor 1, MTS-1, CDKN2, MTS1
- Application:
- ELISA, IHC, WB, IP
- Concentration:
- 85 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Immunogen:
- human p16 protein (missing the first 7 amino acids)
- Format:
- Antiserum
- Uniprot:
- P42771
- Synonyms:
- alternative reading frame;ARF;CDK4 inhibitor p16-INK4;CDK4I;CDKN2;cell cycle negative regulator beta;CMM2;cyclin-dependent kinase 4 inhibitor A;cyclin-dependent kinase inhibitor 2A;cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4);INK4;INK4A;MLM;MTS-1;MTS1;multiple tumor suppressor 1;P14;P14ARF;P16;P16-INK4A;P16INK4;P16INK4A;P19;P19ARF;TP16
- Extra Details:
- The gene for CDK2NA generates several transcripts/proteins which differ from each other in their first exons. Three of these transcripts are generated by alternative splicing (isoform 1 a.k.a p16INK4A, isoform 2 and isoform 3 a.k.a p12), two of which are known to function as inhibitors of CDK4 kinase. One other transcript that is generated from this gene contains an alternate reading frame (ARF), with the first exon located 20kb upstream of the remainder of the gene (isoform 4 a.k.a. p14ARF, p19ARF, ARF). In spite of the structural and some functional differences, all the proteins encoded by the CDKN2A gene are involved in cell cycle G1 control.
- Shipping Conditions:
- Dry Ice