100-401-100
NF-Y Antibody
Cannot supply to this region.
- SKU:
- 100-401-100
- Additional Names:
- NFYA|rabbit anti-NF-Y antibody, Nuclear transcription factor Y subunit alpha, Nuclear transcription factor Y subunit A, NF-YA, CAAT box DNA-binding protein subunit A
- Application:
- ELISA, IHC, WB
- Concentration:
- 90 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Rabbit
- Reactivities:
- Human
- Immunogen:
- NF-Y (A subunit specific) peptide corresponding to a region near the N-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
- Format:
- Antiserum
- Uniprot:
- P23511
- Synonyms:
- CAAT box DNA-binding protein subunit A;CAAT-box DNA binding protein subunit A;CBF-A;CBF-B;CCAAT-binding transcription factor subunit B;HAP2;HAP2 CCAAT-binding protein;NF-YA;nuclear transcription factor Y subunit A;nuclear transcription factor Y subunit alpha;nuclear transcription factor Y, alpha;Transcription factor NF-Y, A subunit
- Extra Details:
- Nuclear transcription factor Y subunit alpha is a protein that in humans is encoded by the NFYA gene. The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. Anti-NF-Y is ideal for investigators involved in transcription factor research.
- Shipping Conditions:
- Dry Ice