100-101-240
Fibrinogen Antibody
Cannot supply to this region.
- SKU:
- 100-101-240
- Additional Names:
- FGA|goat anti-Fibrinogen Antibody, FGA antibody, FGA protein antibody, FGB antibody, FGG antibody, Fib2 antibody, Fibrinogen A alpha polypeptide antibody, Fibrinogen A alpha polypeptide chain antibody, Fibrinogen alpha chain antibody
- Application:
- ELISA, IHC, WB
- Concentration:
- 90 mg/ml
- Physical State:
- Lyophilized
- Species Reactivity:
- Human
- Storage Conditions:
- 2-8[o]C liquid. Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Fibrinogen [Human Plasma]
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Format:
- Antiserum
- Uniprot:
- P02671
- Synonyms:
- Fib2;fibrinogen alpha chain;fibrinogen, A alpha polypeptide
- Extra Details:
- Fibrinogen is cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA), fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, it functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. It was originally thought to be essential for platelet aggregation, based on in vitro studies using anti-coagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. It enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. It may also facilitate the immune response via both innate and T-cell mediated pathways.
- Shipping Conditions:
- Ambient