009-001-B32
IL-17A Human Recombinant Protein
Cannot supply to this region.
- SKU:
- 009-001-B32
- Additional Names:
- IL17A|Interleukin-17 cytokine, IL-17, IL-17A, Interleukin-17A, Cytotoxic T-Lymphocyte-associated Antigen 8, CTLA8.
- Application:
- SDS-PAGE
- Concentration:
- 0.1 mg/ml
- Physical State:
- Lyophilized
- Purity:
- >90%
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Buffer:
- 0.1% Trifluoroacetic acid
- Immunogen:
- IL17A
- Formulation:
- 0.1% Trifluoroacetic acid
- Species:
- Human
- Uniprot:
- Q16552
- Synonyms:
- CTLA-8;CTLA8;cytotoxic T-lymphocyte-associated antigen 8;cytotoxic T-lymphocyte-associated protein 8;IL-17;IL-17A;IL17;ILA17;interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8);interleukin-17;interleukin-17A
- Extra Details:
- Interleukin17-A is a proinflammatory cytokine produced by activated T cells and exists as a homodimer. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. IL-17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL17-A is the founding member of a group of cytokines called the IL-17 family. IL17-A was originally identified as a transcript from a rodent T-cell hybridoma. To elicit its functions, IL17 binds to a type I cell surface receptor called IL17R of which there are at least three variants: IL17RA, IL17RB, and IL17RC.
- Shipping Conditions:
- Ambient