009-001-301
IL-1 Beta Human Recombinant Protein
Cannot supply to this region.
- SKU:
- 009-001-301
- Additional Names:
- IL-1b cytokine, Interleukin 1b, IL-1B Beta, IL-1 beta, Catabolin, H1, Hematopoietin 1, IFN beta inducing factor, Interleukin 1 beta, LAF, OAF, Osteoclast activating factor|IL1B
- Application:
- SDS-PAGE
- Concentration:
- 0.1 mg/ml
- Physical State:
- Lyophilized
- Purity:
- >97%
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Buffer:
- 0.01 M Sodium Phosphate
- Immunogen:
- IL1B
- Formulation:
- 0.01 M Sodium Phosphate, pH 7.5
- Species:
- Human
- Uniprot:
- P01584
- Synonyms:
- catabolin;IL-1;IL-1 beta;IL1-BETA;IL1beta;IL1F2;interleukin 1beta;interleukin-1 beta;preinterleukin 1 beta;pro-interleukin-1-beta
- Extra Details:
- Interleukin-1beta (IL-1B Beta) is a proinflammatory cytokine produced in response to inflammatory agents by a variety of cells, including monocytes, macrophages, and dendric cells (DCs). IL-1B Beta and IL-1A Alpha are two distinct and independently regulated gene products that comprise IL-1 and signal through the Type 1 IL-1 receptor (IL-1R1). Although IL-1A Alpha is cell associated and IL-1B Beta is secreted, they have nearly identical biological activity in that they induce adhesion molecule expression on epithelial cells, control fever induction, and play a role in arthritis and septic shock. Signaling activated by the IL-1R1 promotes these activities through a MYD88 signaling pathway similar to those associated with Toll receptors. Recombinant human IL-1B Beta is a non-glycosylated single chain 17,376 Da protein containing 153 amino acid residues.
- Shipping Conditions:
- Ambient