000-001-GS4
Hemoglobin A (beta chain) Control Peptide
Cannot supply to this region.
- SKU:
- 000-001-GS4
- Additional Names:
- HbB Beta Control Peptide, Hemoglobin beta subunit, HBB, Sickle Cell Disease (SCD)
- Concentration:
- 1 mg/ml
- Physical State:
- Lyophilized
- Purity:
- >95%
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Species:
- Human
- Uniprot:
- P68871
- Synonyms:
- beta globin chain;beta-globin;CD113t-C;ECYT6;Hemoglobin beta chain;hemoglobin beta subunit;hemoglobin subunit beta;hemoglobin, beta
- Extra Details:
- HbA peptide correspond to the hemoglobin beta subunit wild type variant A isoform. Functional adult hemoglobin (Hb) is a hetero tetramer composed of 2 alpha and 2 beta subunits (A Alpha2B Beta2). Common isoform variants of hemoglobin include HbA, HbS, HbC, HbF, and HbA2. Sickle cell disease (SCD), thalassemias and hemoglobinopathies occur when aberrant forms of hemoglobin are expressed in children and adults. Globin gene mutations affect the structure and expression levels of Hb. Sickle cell disease and the more benign sickle cell trait are observed in more than 100 million people globally. Perhaps the most significant mutation is the E6V in the beta subunit and the cause of SCD, but other relevant isoforms of Hb are observed. HbA peptide can be used as a control with the HbA antibody. This peptide is ideal for investigators involved in Cardiovascular and developmental biology research.
- Shipping Conditions:
- Ambient