000-001-E71
AKT2 Control Peptide
Cannot supply to this region.
- SKU:
- 000-001-E71
- Additional Names:
- AKT 2, AKT-2, PKB, PKB beta, PKBBETA PRKBB, Protein kinase Akt 2, Protein kinase B beta, RAC-beta serine/threonine-protein kinase, RAC-PK-beta, blocking peptide|AKT2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Physical State:
- Lyophilized
- Purity:
- >98%
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Immunogen:
- AKT2
- Species:
- Human
- Uniprot:
- P31751
- Synonyms:
- HIHGHH;murine thymoma viral (v-akt) homolog-2;PKB beta;PKBB;PKBBETA;PRKBB;protein kinase Akt-2;protein kinase B beta;putative v-akt murine thymoma viral oncoprotein 2;rac protein kinase beta;RAC-BETA;RAC-beta serine/threonine-protein kinase;RAC-PK-beta;v-akt murine thymoma viral oncogene homolog 2
- Extra Details:
- AKT2 Control peptide is for use in control assays with Anti-AKT2 (p/n 200-501-E71). AKT2 Antibody detects AKT2 which is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis; (ii) promotion of proliferation.
- Shipping Conditions:
- Ambient