000-001-B98
DbpA Control Protein
Cannot supply to this region.
- SKU:
- 000-001-B98
- Additional Names:
- dbpA, BB_A24|Decorin-binding Protein A, Borrelia burgdorferi dbpA, control protein, DbpA Control Protein
- Application:
- ELISA, SDS-PAGE, WB, Functional Assay
- Physical State:
- Liquid
- Purity:
- >90%
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- dbpA, BB_A24
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Species:
- Bacteria
- Uniprot:
- O50917
- Synonyms:
- BB_A24;BB_RS05215;decorin-binding protein DbpA
- Extra Details:
- DbpA, or Decorin Binding Protein A is from the spirochete Borrelia burgdorferi, which is carried by Ixodes ticks. DbpA from other microbial organisms such as E. coli (ATP-dependent RNA helicase DbpA) are significantly different. The spirochete migrates from the tick midgut during tick feeding to tick salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. Spirochetal surface adhesions mediate attachment to decorin, a major component of the host extracellular matrix, enabling bacteria to colonize in mammalian tissues. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host. Lyme disease proteins are ideal for researchers interested in immunology, neurology, rheumatology, coinfections, autoimmune, and neurodegenerative diseases.
- Shipping Conditions:
- Dry Ice