![Near-Infrared DyLight[R] 747 Tracer in vivo Active Caspase (VAD) Assay](https://cdn.shopify.com/s/files/1/0014/8806/0475/files/9114_figure_1.jpg?v=1709769427)
9114
Near-Infrared DyLight[R] 747 Tracer in vivo Active Caspase (VAD) Assay
Size
£527.00
- SKU:
- 9114
- Application:
- Flow Cytometry, IM
- Physical State:
- Tissue
- Purification:
- IN VIVO MONITORING OF APOPTOSIS DURING EXPERIMENTAL ANTI-CANCER TREATMENT, Apoptotic tissues in murine tumor models were imaged in vivo with NIR-FLIVO® 747 Tracer (*Dylight® 747-VAD-FMK, kit #9114) using the CRi Maestro™ imaging system. NIR-FLIVO 747 was used to non-invasively monitor the efficacy and time kinetics of an experimental anti-cancer treatment. After receiving a placebo or an experimental treatment, negative control mice (left image) and experimentally treated mice (right image) were injected intravenously with NIR-FLIVO 747 Tracer and imaged non-invasively at various time points with the CRi Maestro™ imaging system. Apoptotic tumor tissues fluoresce bright blue in the experimental group subjects, indicating that the experimental treatment had an apoptotic effect.
- Storage Conditions:
- -20[o]C
- Supplier:
- ImmunoChemistry Technologies
- Immunogen:
- Poly Caspases
- Extra Details:
- A fluorescent, cell-permeable tracer for the non-invasive measurement of caspase activity in live animals. The Val-Ala-Asp caspase binding sequence gives the DyLight® 747-VAD-FMK Tracer reagent broad caspase reactivity. Dylight® is a registered trademark of Thermo Fisher Scientific, Inc., ICT
- Shipping Conditions:
- Blue Ice