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9112

Near-Infrared DyLight[R] 690 Tracer in vivo Active Caspase (VAD) Assay

Size

£527.00

SKU:
9112
Application:
Flow Cytometry, IM
Physical State:
Tissue
Purification:
Brain abscesses were induced in mice following the intracerebral inoculation of live Staphylococcus aureus. Animals received intravenous injections of NIR-FLIVO 690 Tracer (kit #9112) or NIR-FLIVO 690 Free Dye Control (kit #9113) at 17 hours post-infection, whereupon signals were acquired 1 hour later from brain tissues ex vivo using an IVIS® Spectrum™ (Caliper Life Sciences). Strong caspase activity was associated with brain abscesses following administration of the NIR-FLIVO 690 Tracer (right image), whereas minimal signal was detected in animals injected with the NIR-FLIVO 690 Free Dye Control (left image).
Storage Conditions:
-20[o]C
Supplier:
ImmunoChemistry Technologies
Immunogen:
Poly Caspases
Extra Details:
A fluorescent, cell-permeable tracer for the non-invasive measurement of caspase activity in live animals. The Val-Ala-Asp caspase binding sequence gives the DyLight® 690-VAD-FMK Tracer reagent broad caspase reactivity. Dylight® is a registered trademark of Thermo Fisher Scientific, Inc., ICT
Shipping Conditions:
Blue Ice