GTX89995-PEP
SOCS1 blocking peptide
Cannot supply to this region.
- SKU:
- GTX89995-PEP
- Additional Names:
- Suppressor Of Cytokine Signaling 1 , Cis1 , Cish1 , Jab , Socs-1 , Ssi-1 , Ssi1 , Tip-3 , Tip3 , Socs1
- Physical State:
- Lyophilized
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- suppressor of cytokine signaling 1
- Species:
- Human
- Synonyms:
- AISIMD;CIS1;CISH1;cytokine-inducible SH2 protein 1;JAB;JAK binding protein;SOCS-1;SSI-1;SSI1;STAT induced SH3 protein 1;STAT-induced STAT inhibitor 1;suppressor of cytokine signaling 1;Tec-interacting protein 3;TIP-3;TIP3
- Extra Details:
- This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice