GTX89965
DOCK1 antibody, C-term
Cannot supply to this region.
- SKU:
- GTX89965
- Additional Names:
- dedicator of cytokinesis 1 , DOCK180 , ced5
- Application:
- WB
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-TTRKQTSVDSGIVQ, from the C Terminus of the protein sequence according to NP_001371.1.
- Uniprot:
- Q14185
- Synonyms:
- 180 kDa protein downstream of CRK;ced5;dedicator of cytokinesis protein 1;DOCK180;DOwnstream of CrK
- Extra Details:
- This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
- Shipping Conditions:
- Blue Ice