DUSP8 antibody, N-term

Cannot supply to this region.

SKU:: GTX89940
Additional Names:: dual specificity phosphatase 8 , C11orf81 , HB5 , HVH-5 , HVH8
Application:: WB
Concentration:: 0.50 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Ammonium Sulfate Precipitated; Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Goat
Reactivities:: Human, Mouse, Rat
Buffer:: TBS, 0.5% BSA, 0.02% Sodium azide.
Immunogen:: Peptide with sequence AGDRLPRKVMDAK-C, from the N Terminus of the protein sequence according to NP_004411.2.
Uniprot:: Q13202
Synonyms:: C11orf81;dual specificity protein phosphatase 8;dual specificity protein phosphatase hVH-5;H1 phosphatase, vaccinia virus homolog;HB5;HVH-5;HVH8;serine/threonine specific protein phosphatase
Extra Details:: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice