GTX89916
LIS1 antibody, C-term
Cannot supply to this region.
- SKU:
- GTX89916
- Additional Names:
- platelet activating factor acetylhydrolase 1b regulatory subunit 1 , LIS1 , LIS2 , MDCR , MDS , NudF , PAFAH
- Application:
- WB, IHC-P
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human, Rat
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence TGSVDQTVKVWECR, from the C Terminus of the protein sequence according to NP_000421.1.
- Uniprot:
- P43034
- Synonyms:
- LIS1;LIS2;lissencephaly 1 protein;Lissencephaly-1 protein;MDCR;MDS;NudF;PAF acetylhydrolase 45 kDa subunit;PAF-AH alpha;PAFAH;platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa);platelet-activating factor acetylhydrolase IB subunit beta
- Extra Details:
- This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009]
- Shipping Conditions:
- Blue Ice