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GTX89893-PEP

SAP130 blocking peptide

Cannot supply to this region.

SKU:
GTX89893-PEP
Additional Names:
Splicing Factor 3B Subunit 3 , Rse1 , Sap130 , Sf3B130 , Staf130 , Sf3B3
Physical State:
Lyophilized
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Buffer:
Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:
splicing factor 3b subunit 3
Species:
Human
Synonyms:
pre-mRNA splicing factor SF3b, 130 kDa subunit;RSE1;SAP 130;SAP130;SF3b130;spliceosome-associated protein 130;splicing factor 3B subunit 3;STAF130
Extra Details:
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice