BCAR3 antibody, C-term

Cannot supply to this region.

SKU:: GTX89796
Additional Names:: BCAR3 adaptor protein, NSP family member , AND-34 , NSP2 , SH2D3B
Application:: WB
Concentration:: 0.50 mg/ml
Physical State:: Liquid
Species Reactivity:: Human, Mouse
Purification:: Ammonium Sulfate Precipitated; Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Goat
Reactivities:: Mouse
Buffer:: TBS, 0.5% BSA, 0.02% Sodium azide.
Immunogen:: Peptide with sequence C-RKLEPPPVKQAEL, from the C Terminus of the protein sequence according to NP_003558.1.
Uniprot:: O75815
Synonyms:: AND-34;BCAR3, NSP family adaptor protein;breast cancer anti-estrogen resistance 3;breast cancer anti-estrogen resistance protein 3;breast cancer antiestrogen resistance 3 protein;dJ1033H22.2 (breast cancer anti-estrogen resistance 3);epididymis secretory sperm binding protein;mig-7;MIG7;migration inducting gene-7;novel SH2-containing protein 2;NSP2;SH2 domain-containing protein 3B;SH2D3B
Extra Details:: Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Shipping Conditions:: Blue Ice