GTX89716-PEP
PI3 kinase C2 alpha blocking peptide

Cannot supply to this region.
- SKU:
- GTX89716-PEP
- Additional Names:
- Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha , Cpk , Pi3-K-C2(Alpha) , Pi3-K-C2A , Pi3K-C2-Alpha , Pi3K-C2Alpha , Pik3C2A
- Physical State:
- Lyophilized
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
- Species:
- Human
- Synonyms:
- C2-containing phosphatidylinositol kinase;CPK;OCSKD;phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha;phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha;phosphoinositide 3-kinase-C2-alpha;phosphoinositide-3-kinase, class 2, alpha polypeptide;PI3-K-C2(ALPHA);PI3-K-C2A;PI3K-C2-alpha;PI3K-C2alpha;ptdIns-3-kinase C2 subunit alpha
- Extra Details:
- The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice
