GTX89661
LXR beta antibody, N-term
Cannot supply to this region.
- SKU:
- GTX89661
- Additional Names:
- nuclear receptor subfamily 1 group H member 2 , LXR-b , LXRB , NER , NER-I , RIP15 , UNR
- Application:
- WB, IHC-P
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence SSPTTSSLDTPLPGC, from the N Terminus of the protein sequence according to NP_009052.3.
- Uniprot:
- P55055
- Synonyms:
- liver X nuclear receptor beta;Liver X receptor beta;LX receptor beta;LXR-b;LXRB;NER;NER-I;nuclear orphan receptor LXR-beta;nuclear receptor NER;Nuclear receptor subfamily 1 group H member 2;oxysterols receptor LXR-beta;RIP15;steroid hormone-nuclear receptor NER;ubiquitously-expressed nuclear receptor;UNR
- Extra Details:
- The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
- Shipping Conditions:
- Blue Ice