GTX89660
DOK5 antibody, C-term
Cannot supply to this region.
- SKU:
- GTX89660
- Additional Names:
- docking protein 5 , C20orf180 , IRS-6 , IRS6
- Application:
- WB, IHC-P
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence CLHRTETFPAYRSEH, from the C Terminus of the protein sequence according to NP_060901.2.
- Uniprot:
- Q9P104
- Synonyms:
- C20orf180;docking protein 5;downstream of tyrosine kinase 5;insulin receptor substrate 6;IRS-6;IRS6
- Extra Details:
- The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2014]
- Shipping Conditions:
- Blue Ice