Sorbitol Dehydrogenase blocking peptide

Cannot supply to this region.

SKU:: GTX89635-PEP
Additional Names:: Sorbitol Dehydrogenase , Hel-S-95N , Sord1 , Sord
Physical State:: Lyophilized
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:: sorbitol dehydrogenase
Species:: Human
Synonyms:: (R,R)-butanediol dehydrogenase;epididymis secretory sperm binding protein Li 95n;HEL-S-95n;L-iditol 2-dehydrogenase;polyol dehydrogenase;RDH;ribitol dehydrogenase;SDH;sorbitol dehydrogenase;SORD1;SORDD;XDH;xylitol dehydrogenase
Extra Details:: Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]