GTX89599
SCAP2 antibody, C-term
Cannot supply to this region.
- SKU:
- GTX89599
- Additional Names:
- src kinase associated phosphoprotein 2 , PRAP , RA70 , SAPS , SCAP2 , SKAP-HOM , SKAP55R
- Application:
- WB
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-GLVPKAYIMEMYDI, from the C Terminus of the protein sequence according to NP_003921.2.
- Uniprot:
- O75563
- Synonyms:
- Fyn-associated phosphoprotein SKAP55 homologue;PRAP;Pyk2/RAFTK-associated protein;RA70;retinoic acid-induced protein 70;SAPS;SCAP2;SKAP-55HOM;SKAP-HOM;SKAP55 homolog;SKAP55R;src family-associated phosphoprotein 2;src kinase-associated phosphoprotein 2;Src kinase-associated phosphoprotein 55-related protein;src kinase-associated phosphoprotein of 55-related protein;src-associated adapter protein with PH and SH3 domains
- Extra Details:
- The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
- Shipping Conditions:
- Blue Ice