GTX89476
NOTCH3 antibody, C-term
Cannot supply to this region.
- SKU:
- GTX89476
- Additional Names:
- notch receptor 3 , CADASIL , CADASIL1 , CASIL , IMF2 , LMNS
- Application:
- IHC-P
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-QLGPQPEVTPKRQ, from the C Terminus of the protein sequence according to NP_000426.2.
- Uniprot:
- Q9UM47
- Synonyms:
- CADASIL;CADASIL1;CASIL;IMF2;LMNS;neurogenic locus notch homolog protein 3;notch 3;Notch homolog 3
- Extra Details:
- This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice