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  2. Polyclonal

GTX89365

CYP17A1 antibody, Internal

Cannot supply to this region.

SKU:
GTX89365
Additional Names:
cytochrome P450 family 17 subfamily A member 1 , CPT7 , CYP17 , P450C17 , S17AH
Application:
WB, IHC-P
Concentration:
0.50 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Ammonium Sulfate Precipitated; Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Goat
Reactivities:
Human
Buffer:
TBS, 0.5% BSA, 0.02% Sodium azide.
Immunogen:
Peptide with sequence C-LFKDGDQKLEK, from the internal region of the protein sequence according to NP_000093.1.
Uniprot:
P05093
Synonyms:
17-alpha-hydroxyprogesterone aldolase;CPT7;CYP17;CYPXVII;cytochrome P450 17A1;cytochrome p450 XVIIA1;cytochrome P450-C17;cytochrome P450, family 17, subfamily A, polypeptide 1;cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia;cytochrome P450c17;P450C17;S17AH;steroid 17-alpha-hydroxylase/17,20 lyase;steroid 17-alpha-monooxygenase
Extra Details:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice