GTX89269
Munc 13-4 antibody, Internal
Cannot supply to this region.
- SKU:
- GTX89269
- Additional Names:
- unc-13 homolog D , FHL3 , HLH3 , HPLH3 , Munc13-4
- Application:
- WB, IHC-P
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human, Mouse
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-ETQKHKKDLHPLFD, from the internal region of the protein sequence according to NP_954712.1.
- Uniprot:
- Q70J99
- Synonyms:
- FHL3;HLH3;HPLH3;Munc13-4;protein unc-13 homolog D
- Extra Details:
- This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice