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  2. Polyclonal

GTX89246

FLAP antibody, Internal

Cannot supply to this region.

SKU:
GTX89246
Additional Names:
arachidonate 5-lipoxygenase activating protein , FLAP
Application:
WB, IHC-P
Concentration:
0.50 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Ammonium Sulfate Precipitated; Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Goat
Reactivities:
Human
Buffer:
TBS, 0.5% BSA, 0.02% Sodium azide.
Immunogen:
Peptide with sequence C-HKVEHESRTQNGR, from the internal region of the protein sequence according to NP_001620.2; NP_001191335.1.
Uniprot:
P20292
Synonyms:
arachidonate 5-lipoxygenase-activating protein;FLAP;MK-886-binding protein
Extra Details:
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
Shipping Conditions:
Blue Ice