Cav beta 4 antibody, Internal

Cannot supply to this region.

SKU:: GTX89203
Additional Names:: calcium voltage-gated channel auxiliary subunit beta 4 , CAB4 , CACNLB4 , EA5 , EIG9 , EJM , EJM4 , EJM6
Application:: WB
Concentration:: 0.50 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Ammonium Sulfate Precipitated; Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Goat
Reactivities:: Human
Buffer:: TBS, 0.5% BSA, 0.02% Sodium azide.
Immunogen:: Peptide with sequence C-DYPDSYQDTYKPH, from the internal region (near the C Terminus) of the protein sequence according to NP_001005747.1; NP_000717.2; NP_001005746.1.
Uniprot:: O00305
Synonyms:: CAB4;CACNLB4;calcium channel voltage-dependent subunit beta 4;dihydropyridine-sensitive L-type, calcium channel beta-4 subunit;EA5;EIG9;EJM;EJM4;EJM6;voltage-dependent L-type calcium channel subunit beta-4
Extra Details:: This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE), juvenile myoclonic epilepsy (JME), and episodic ataxia, type 5. [provided by RefSeq, Aug 2016]

Shipping Conditions:: Blue Ice