GTX89181-PEP
NR1H4 blocking peptide
Cannot supply to this region.
- SKU:
- GTX89181-PEP
- Additional Names:
- Nuclear Receptor Subfamily 1 Group H Member 4 , Bar , Fxr , Hrr-1 , Hrr1 , Pfic5 , Rip14 , Nr1H4
- Physical State:
- Lyophilized
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- nuclear receptor subfamily 1 group H member 4
- Species:
- Human
- Synonyms:
- BAR;bile acid receptor;farnesoid X nuclear receptor;farnesoid X-activated receptor;farnesol receptor HRR-1;FXR;HRR-1;HRR1;PFIC5;retinoid X receptor-interacting protein 14;RIP14;RXR-interacting protein 14
- Extra Details:
- This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
- Shipping Conditions:
- Blue Ice