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GTX89061-PEP

SHP1 (internal) blocking peptide

Cannot supply to this region.

SKU:
GTX89061-PEP
Additional Names:
Protein Tyrosine Phosphatase, Non-Receptor Type 6 , Hcp , Hcph , Hptp1C , Ptp-1C , Sh-Ptp1 , Shp-1 , Shp-1L , Shp1 , Ptpn6
Physical State:
Lyophilized
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Buffer:
Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:
protein tyrosine phosphatase, non-receptor type 6
Species:
Human
Synonyms:
HCP;HCPH;hematopoietic cell phosphatase;hematopoietic cell protein-tyrosine phosphatase;HPTP1C;protein-tyrosine phosphatase 1C;protein-tyrosine phosphatase SHP-1;PTP-1C;SH-PTP1;SHP-1;SHP-1L;SHP1;tyrosine-protein phosphatase non-receptor type 6
Extra Details:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice