TIA1 blocking peptide

Cannot supply to this region.

SKU:: GTX89059-PEP
Additional Names:: Tia1 Cytotoxic Granule Associated Rna Binding Protein , Tia-1 , Wdm , Tia1
Physical State:: Lyophilized
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:: TIA1 cytotoxic granule-associated RNA binding protein
Species:: Human
Synonyms:: ALS26;nucleolysin TIA-1;nucleolysin TIA-1 isoform p40;p40-TIA-1 (containing p15-TIA-1);T-cell-restricted intracellular antigen-1;TIA-1;WDM
Extra Details:: The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq, Jul 2008]