GTX88924-PEP
WISP1 blocking peptide
Cannot supply to this region.
- SKU:
- GTX88924-PEP
- Additional Names:
- Wnt1 Inducible Signaling Pathway Protein 1 , Ccn4 , Wisp1-Ot1 , Wisp1-Ut1 , Wisp1C , Wisp1I , Wisp1Tc , Wisp1
- Physical State:
- Lyophilized
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- WNT1 inducible signaling pathway protein 1
- Species:
- Human
- Synonyms:
- CCN family member 4;WISP1;WISP1 3'UTR-associated RNA 1;WISP1 overlapping transcript 1 (non-protein coding);WISP1-OT1;WISP1-UT1;WISP1c;WISP1i;WISP1tc;WNT1 induced secreted protein 1;WNT1 inducible signaling pathway protein 1
- Extra Details:
- This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-media
- Shipping Conditions:
- Blue Ice