GTX88845-PEP
Kir6.2 blocking peptide
Cannot supply to this region.
- SKU:
- GTX88845-PEP
- Additional Names:
- Potassium Voltage-Gated Channel Subfamily J Member 11 , Bir , Hhf2 , Ikatp , Kir6.2 , Mody13 , Phhi , Tndm3 , Kcnj11
- Physical State:
- Lyophilized
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- potassium voltage-gated channel subfamily J member 11
- Species:
- Human
- Synonyms:
- ATP-sensitive inward rectifier potassium channel 11;beta-cell inward rectifier subunit;BIR;HHF2;IKATP;inward rectifier K(+) channel Kir6.2;inwardly rectifing potassium channel subfamily J member 11;inwardly rectifying potassium channel KIR6.2;inwardly-rectifying potassium channel subfamily J member 11;KIR6.2;MODY13;PHHI;PNDM2;potassium channel inwardly rectifing subfamily J member 11;potassium channel, inwardly rectifying subfamily J member 11;potassium voltage-gated channel subfamily J member 11;TNDM3
- Extra Details:
- Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2009]
- Shipping Conditions:
- Blue Ice