GTX88691-PEP
MRP5 blocking peptide
Cannot supply to this region.
- SKU:
- GTX88691-PEP
- Additional Names:
- Atp Binding Cassette Subfamily C Member 5 , Abc33 , Est277145 , Moat-C , Moatc , Mrp5 , Smrp , Pabc11 , Abcc5
- Physical State:
- Lyophilized
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- ATP binding cassette subfamily C member 5
- Species:
- Human
- Synonyms:
- ABC33;ATP-binding cassette, sub-family C (CFTR/MRP), member 5;canalicular multispecific organic anion transporter C;EST277145;MOAT-C;MOATC;MRP5;multi-specific organic anion transporter C;multidrug resistance-associated protein 5;pABC11;SMRP
- Extra Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected; however, the complete seq
- Shipping Conditions:
- Blue Ice