GCH1 blocking peptide

Cannot supply to this region.

SKU:: GTX88689-PEP
Additional Names:: Gtp Cyclohydrolase 1 , Dyt14 , Dyt5 , Dyt5A , Gch , Gtp-Ch-1 , Gtpch1 , Hpabh4B , Gch1
Physical State:: Lyophilized
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:: GTP cyclohydrolase 1
Species:: Human
Synonyms:: dystonia 14;DYT14;DYT5;DYT5a;GCH;GTP cyclohydrolase 1;GTP cyclohydrolase I;GTP-CH-1;GTP-CH-I;GTPCH1;guanosine 5'-triphosphate cyclohydrolase I;HPABH4B
Extra Details:: This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008]