GTX88502
Muscleblind-like 1 antibody, C-term
Cannot supply to this region.
- SKU:
- GTX88502
- Additional Names:
- muscleblind like splicing regulator 1 , EXP , MBNL
- Application:
- WB
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-SAEHLTSHKYVTQ , from the C Terminus of the protein sequence according to NP_066368.2; NP_997175.1; NP_997176.1; NP_997177.1; NP_997178.1; NP_997179.1; NP_997180.1.
- Uniprot:
- Q9NR56
- Synonyms:
- EXP;MBNL;muscleblind-like;muscleblind-like protein 1;triplet-expansion RNA-binding protein
- Extra Details:
- This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015]
- Shipping Conditions:
- Blue Ice