GTX88466-PEP
ITM2B blocking peptide
Cannot supply to this region.
- SKU:
- GTX88466-PEP
- Additional Names:
- Integral Membrane Protein 2B , Abri , Bri , Bri2 , Bricd2B , E25B , E3-16 , Fbd , Rdgca , Imbri2 , Itm2B
- Physical State:
- Lyophilized
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- integral membrane protein 2B
- Species:
- Human
- Synonyms:
- ABRI;ABri/ADan amyloid peptide;BRI;BRI2;BRICD2B;BRICHOS domain containing 2B;E25B;E3-16;epididymis secretory sperm binding protein;FBD;imBRI2;immature BRI2;integral membrane protein 2B;RDGCA;transmembrane protein BRI
- Extra Details:
- Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009]
- Shipping Conditions:
- Blue Ice